- GBS is a clinical diagnosis! Don’t wait with treatment untill all assessments have been done
- EMG
- Lumbar puncture after brain imaging: typically elevated protein with normal white blood cell count
- CMV, mycoplasma, hepatitis E, campylobacter jejuni serology, check presence of anti-GQ1b antibodies
- Swallowing analysis
- Pulmonary function tests with vital capacity and maximum inspiratory/expiratory pressures; respiratory function should be evaluated 6 x pd
- ECG

- IVIg therapy
- Plasmapheresis or IVIg therapy might be repeated
- FU in accordance with local neurologists
- Corticoid treatment discussion
- Consider location of care where ventilatory support is available (required in 15-30% of idiopathic cases)
- Close FU of patient: monitoring of respiratory function at least 6 x pd + (ECG) monitoring in order to detect autonomic dysfunction
- DVT prevention

Not indicated for idiopathic GBS, however some case reports show interesting results with ICPI induced GBS with methylprednisolone 1-2mg/kg (check literature). Among the neurology community discussion is ongoing if ICPI induced GBS is similar to chronic inflammatory demyelinating polyneuropathy (CIDP). The latter has a similar symptoms as GBS but has a slower onset and in contrast to GBS, for CIDP corticoids are indicated.