Muscle pathology – Patient unstable
October 17, 2026Muscle pathology – Patient stable – Severe Yes
October 29, 2026Myocarditis algorithm – Stable patient
Assess severity + IC-OS diagnostic criteria for myocarditis
Diagnostic confirmation (IC-OS criteria) ?
IC-OS myocarditis diagnostic criteria:
- Histological diagnosis
OR
- Clinical diagnosis (Troponin elevation AND 1 major criteria OR 3 minor criteria)
- Major criteria: positive MRI (Lake Louise criteria)
- Minor criteria
- Cardiomuscular symptoms
- Ventricular arrythmia or new conduction block
- Decline in LVEF
- Presence of myositis or other irAE
- suggestive MRI
Severe if any of:
- Symptomatic patients.
- Troponin > 32* ULN.
- New LVEF degradation.