PF Joint Toxicity
April 19, 2025PF 1.1.1 Arthralgia – Grade 1
April 20, 2025Arthralgia
Symptom Grade 1
- No clinical swelling
- Joint pain
- Stiffness
Management escalation pathway
- Initiate analgesia with paracetamol and/or NSAID (If not contraindicated)
- Continue ICPI
Assessment and Investigations
- Complete rheumatological history
- Examination of all joints and skin
- Consider imaging to exclude metastases
- Consider ultrasound to exclude artritis
Symptom Grade 2
- Moderate or severe pain limiting daily activities
- Signs of inflammatory arthralgia (pain at rest, pain worsening with exercise)
Management escalation pathway
- Initiate analgesia with paracetamol and/or NSAID (If not contraindicated)
- Continue ICPI
Assessment and Investigations
- Complete rheumatological history
- Examination of all joints and skin
- Consider imaging to exclude metastases
- Consider ultrasound to exclude artritis