Skin toxicity – Grade 2-4 – Low risk
Assessment and investigations
- Perform anamnesis, clinical assessment, and basic lab test
Management escalation pathway
- Treat ambulatory
- Apply topical steroids as indicated
- Apply symptomatic treatment to associated symptoms (e.g. itching, dry skin) as indicated second-generation antihistamines
- If symptoms persist > 6 days consult dermatologist
Symptoms resolved to grade 0 or 1?
Yes:
- Stop topical therapy
- Restart ICPI
No:
- biopsy should be done
Abbrevations:
BSA: Body Surface Area
ADL: Activities of Daily Living
BW: Body Weight
ICU: Intensive Care Unit
