Muscle pathology
Polymyalgia rheumatica
- Typically inflammatory girdle (shoulder and pelvic) stiffness and pain
Myositis
- Muscle weakness
- Muscle pain
- CK elevationv
Alarm symptoms:
- Diaphragm paralysis
- Concomitant myocarditis
- Swallowing troubles
- Diplopia
- Dyspnea due to respiratory muscle involvement
Myastenia gravis
- Fluctuating muscle weakness (proximal limb, trunk, ocular, e.g. ptosis/diplopia or bulbar)
- Respiratory muscles may also be involved
Fatigability:
Muscle weakness is induced and aggravated by exercise
Abbrevations
ACPA: Anti Citrullinated Antibody
ANF: Anti Nuclear Factor
C3/C4: Complement Factor 3 or 4
CK: Creatine Kinase
CK MB: Creatine Kinase Muscle
ECG: ElectroCardioGram
EMG: ElectroMyoGram
ICPi: Immune Checkpoint Blockade Inhibition
MRI: Magnetic Resonance Imaging
PD: Per Day
PO: Per Os
Pro-BNP: Pro-Brain Natriuretic Peptide
RF: Rheuma Factor
ULN: Upper Limit of Normal
In collaboration with
Rhumato-onco taskforce KBVR/SRBR (Yves Piette, Ellen Delanghe)
Gauthier Remiche, ULB Erasme
Olivier Lambotte, AP-HP, Hôpital Bicêtre, Service de Médecine Interne et Immunologie Clinique, Paris, France
Dimitri Psimaras, Praticien Hospitalier, Département de Neurologie Mazarin, GHPS, Paris, France
Note: This is not a diagnosis/management tool for patients: patients should always consult their treating specialist