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Belgian Multidisciplinary Immunotoxicity Board (BITOX)
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Colitis
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Colitis – Grade 2
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Colitis – Grade 2 – Low risk
Colitis – Grade 2 – Low risk
Treat ambulatory
Initiate oral methylprednisolone at a dose of 2x 32 mg per day, start first dose in hospital.
Initiate oral antibiotics (e.g. ciproxin 250 mg BID) in case of suspected infectious origin and adapt according to result of coproculture
Did the diarrhea stop within 72h and no recurrence on day 4 and 5?
Yes
No
Abbreviations
Abbrevations:
H:
Hematology
C:
Chemistry
ICPi:
Immune Checkpoint Blockade Inhibition
Hb:
Hemoglobin
CRP:
C Reactive Protein
BP:
Blood Pressure
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