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Hypothyroidism – Subclinical
Hypothyroidism – Subclinical
Subclinical
Clinical
Severe
Management
Pursue ICPI
Start standard thyroid hormone replacement therapy if TSH > 10 mIU/L with normal free T4
Assessment and Investigations
Repeat TSH and free T4 testing after 6-8 weeks and adjust thyroid hormone dose accordingly.
If TSH is above reference range, increase thyroid hormone dose by 12,5 mcg to 25 mcg.
After identification of the appropriate maintenance dose, further evaluation is required every year, or sooner if patient’s status changes.
Abbreviations
Abbrevations:
ICPi:
Immune Checkpoint Blockade Inhibition
TSH:
Thyroid-Stimulating Hormone
FT4:
Free Thyroxin
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